Genome-wide association study in European patients with congenital heart disease identifies risk loci for transposition of the great arteries and anomalies of the thoracic arteries and veins and expression of discovered candidate genes in the developing heart
Harald Lahm, Meiwen Jia, Martina Dreßen, Felix Wirth, Nazan Puluca, Ralf Gilsbach, Bernard D. Keavney, Julie Cleuziou, Nicole Beck, Olga Bondareva, Elda Dzilic, Melchior Burri, Karl Christian König, Johannes Amadeus Ziegelmueller, Claudia Abou‐Ajram, , Markus Krane
This study identifies genetic risk loci for congenital heart disease subtypes and shows candidate genes play essential roles in heart development.
Journal of Clinical Investigation · Nov 17, 2020Peer-reviewedGenomics