Reliance of neuronal gene expression on cohesin scales with chromatin loop length
Lesly Calderón, Felix D. Weiss, Jonathan A Beagan, Marta S Oliveira, Radina Georgieva, Yi-Fang Wang, Thomas S Carroll, Gopuraja Dharmalingam, Wanfeng Gong, Kyoko Tossell, Vincenzo De Paola, Chad Whilding, Mark A Ungless, Amanda G. Fisher, Jennifer E Phillips-Cremins, Matthias Merkenschlager
The paper shows that cohesin's role in neuronal gene expression depends on chromatin loop length, with longer loops requiring cohesin for full gene expression.
eLife · Apr 26, 2022Peer-reviewedGenomics