Author

Radina Georgieva

Imperial College LondonORCID 0000-0002-2241-2175Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Matthias MerkenschlageriD· 2 shared Yi-Fang WangiD· 2 shared Alex MontoyaiD· 1 shared Amanda G. FisheriD· 1 shared Chad Whilding· 1 shared David RuedaiD· 1 shared Felix D. WeissiD· 1 shared Gopuraja Dharmalingam· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMolecular Biology

Matthias MerkenschlagerORCID

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2 papers

Recent·Most cited

Conserved helical motifs in the Ikaros IDR mediate NuRD interaction and transcriptional repression

Tianyi Zhang, Yi-Fang Wang, Alex Montoya, Nehir Nebioglu, Husayn Ahmed Pallikonda, Radina Georgieva, Ilinca Patrascan, James W. D. King, Holger Kramer, Pavel V. Shliaha, David Rueda, Matthias Merkenschlager

This study identifies conserved helical motifs in Ikaros that mediate NuRD interaction and transcriptional repression in pre-B cells and B-ALL.

bioRxiv · Feb 29, 2024 · PreprintMolecular Biology

Reliance of neuronal gene expression on cohesin scales with chromatin loop length

Lesly Calderón, Felix D. Weiss, Jonathan A Beagan, Marta S Oliveira, Radina Georgieva, Yi-Fang Wang, Thomas S Carroll, Gopuraja Dharmalingam, Wanfeng Gong, Kyoko Tossell, Vincenzo De Paola, Chad Whilding, Mark A Ungless, Amanda G. Fisher, Jennifer E Phillips-Cremins, Matthias Merkenschlager

The paper shows that cohesin's role in neuronal gene expression depends on chromatin loop length, with longer loops requiring cohesin for full gene expression.

eLife · Apr 26, 2022Peer-reviewedGenomics