Author

Gopuraja Dharmalingam

MRC London Institute of Medical Sciences

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

Matthias MerkenschlageriD· 2 shared Ali MortazaviiD· 1 shared Amanda G. FisheriD· 1 shared Amy C. HarmsiD· 1 shared Ana ConesaiD· 1 shared Andreas SchmidtiD· 1 shared Antonio García-GómeziD· 1 shared Axel ImhofiD· 1 shared

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2019-2022 · peak 1/yr

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10 top collaborators · 31 mutual co-author links

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2 shared papersGenomics

Matthias MerkenschlagerORCID

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2 papers

Recent·Most cited

Reliance of neuronal gene expression on cohesin scales with chromatin loop length

Lesly Calderón, Felix D. Weiss, Jonathan A Beagan, Marta S Oliveira, Radina Georgieva, Yi-Fang Wang, Thomas S Carroll, Gopuraja Dharmalingam, Wanfeng Gong, Kyoko Tossell, Vincenzo De Paola, Chad Whilding, Mark A Ungless, Amanda G. Fisher, Jennifer E Phillips-Cremins, Matthias Merkenschlager

The paper shows that cohesin's role in neuronal gene expression depends on chromatin loop length, with longer loops requiring cohesin for full gene expression.

eLife · Apr 26, 2022Peer-reviewedGenomics

STATegra: a comprehensive multi-omics dataset of B-cell differentiation in mouse

David Gómez-Cabrero, Sonia Tarazona, Isabel Ferreirós-Vidal, Ricardo N. Ramírez, Andreas Schmidt, Theo H Reijmers, Veronica von Saint Paul, Francesco Marabita, Javier Rodríguez‐Ubreva, Antonio García-Gómez, Thomas D. Carroll, Lee Cooper, Ziwei Liang, Gopuraja Dharmalingam, Frans M. van der Kloet, , Ana Conesa

The paper presents STATegra, a multi-omics dataset of mouse B-cell differentiation combining 10 omics technologies to study dynamic cellular processes.

Scientific Data · Oct 31, 2019Peer-reviewedBioinformatics