Author

Denisa Bojková

University Hospital FrankfurtORCID 0000-0001-7914-9710Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1

Frequent Co-Authors

Jindrich Jr. CinatliD· 2 shared Sandra CiesekiD· 2 shared Alpha Tom KodamulliliD· 1 shared Andrea ZalianiiD· 1 shared Bernhard BrüneiD· 1 shared Bruce T. SchultziD· 1 shared Carsten ClausseniD· 1 shared Ceri-Ann Brigid Lynch· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

Jindrich Jr. CinatlORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintNov 3, 2025

The Coronavirus Envelope Is Modulated by Host Inflammation and Enriched in Bioactive Lipids Required for Replication

Victoria J. Tyrrell, Ανδρέας Ζαραγκούλιας, Wendy Powell…·Valerie B. O’Donnell

This study characterizes the lipid composition of SARS-CoV-2 envelopes from cultured strains and patient isolates, showing inflammation-induced changes and identifying lipid targets for antiviral and antithrombotic strategies.

DOI 10.1101/2025.11.03.686211

humanproteomics

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BioinformaticsbioRxivPreprintSep 23, 2020

The COVID-19 PHARMACOME: A method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization

Bruce T. Schultz, Andrea Zaliani, Christian Ebeling…·Martin Hofmann‐Apitius

The paper presents a drug-target-mechanism graph to identify synergistic drug combinations for SARS-CoV-2 treatment, validated through experimental testing.

2 citations

humanstatistical model

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Systems BiologyMolecular CellPeer-reviewedAug 11, 2020

Growth factor receptor signaling inhibition prevents SARS-CoV-2 replication

Kevin Klann, Denisa Bojková, Georg Tascher…·Jindrich Jr. Cinatl

This study identifies growth factor receptor signaling as a key pathway for SARS-CoV-2 replication and shows that inhibiting it prevents viral replication in human cells.

237 citationstop 3%

humanproteomics

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