Large adipocytes alter mode of lipid release and promote breast cancer malignancy
Garrett F. Beeghly, Irina Kopyeva, Jenny Deng, Marlee Pincus, Rohan Varshney, Dilip D. Giri, Domenick J. Falcone, Michael C. Rudolph, Marc A. Antonyak, Neil M. Iyengar, Claudia Fischbach
This study shows that large adipocytes release lipids via extracellular vesicles, promoting breast cancer cell migration and proliferation, and links this to human dyslipidemia and triglyceride levels.
Cell Reports · Mar 1, 2026Peer-reviewedCell Biology