Author

Mary Basse

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Aaron R. GoldmaniD· 1 shared Conner R. YorkiD· 1 shared Francesca FerraroiD· 1 shared Judith O. SokeiiD· 1 shared Liana ValiniD· 1 shared Nancy B.J. ArthuriD· 1 shared Nishanth GabrieliD· 1 shared Orsola di MartinoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aaron R. GoldmanORCID

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1 paper

Recent·Most cited

Targeting MTHFD2 disrupts mitochondrial redox homeostasis and restores venetoclax sensitivity in acute myeloid leukemia

Judith O. Sokei, Orsola di Martino, Mary Basse, Nishanth Gabriel, Liana Valin, Conner R. York, Nancy B.J. Arthur, Wujuan Zhang, Aaron R. Goldman, Francesca Ferraro, Stephen Matthew Sykes

This study identifies MTHFD2 as a critical mitochondrial enzyme in AML that supports redox homeostasis and therapeutic resistance, showing that its inhibition restores venetoclax sensitivity.

bioRxiv · Mar 20, 2026 · PreprintCancer Biology