Formation of chromosomal rearrangements in Saccharomyces cerevisiae diploids through regionally-biased non-allelic homologous recombination
Sean A. Merriman, Mary J Chapman, Joseph A. Stewart, Carlo Schmelzer, Rabab Sharif, Megan J Hemmerlein, Christopher M Puccia, Guilherme M. de Mattos, Mackenzie A. Wienke, Déborah Afonso Cornélio, Matthew Dilsaver, Ruth A. Watson, Juan Lucas Argueso
The paper identifies a bias for chromosomal rearrangements at the right arm of Chr7 in yeast, showing that this bias is due to inefficient repair rather than increased breakage.
bioRxiv · May 8, 2025 · PreprintGenetics