Characterization of systemic genomic instability in budding yeast
Nadia M. V. Sampaio, V. P. Ajith, Ruth A. Watson, Lydia R. Heasley, Parijat Chakraborty, Aline Rodrigues-Prause, Ewa P. Malc, Piotr A. Mieczkowski, Koodali T Nishant, Juan Lucas Argueso
The paper characterizes bursts of genome-wide loss-of-heterozygosity in budding yeast, showing non-independent mutation accumulation and systemic genomic instability.
Proceedings of the National Academy of Sciences · Oct 26, 2020Peer-reviewedGenetics