Cell BiologyeLifePeer-reviewed
Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway
Ryosuke Isotani, Masaki Igarashi, Masaomi Miura…·Toshimasa Yamauchi
This study shows nicotine increases intestinal stem cell stemness and tumorigenicity through Hippo-YAP/TAZ and Notch pathways, and suggests DBZ as a potential therapeutic.
14 citations