Author

Mathias Madalinski

Institute of Molecular Biotechnology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Fränze MülleriD· 2 shared Karl MechtleriD· 2 shared Manuel MatzingeriD· 2 shared Adrian Vasiu· 1 shared Bogdan R. BrutiuiD· 1 shared Dalia Barsyte-LovejoyiD· 1 shared Florian StanekiD· 1 shared Iakovos SaridakisiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

Fränze MüllerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Oncogenic E3-ligase adaptors MAGE-A3/6 promote cancer cell migration via BAP18 degradation

Maximilian W. G. Schneider, Marie S Polgar, Robert Kalis, Philip Barbulescu, Natalia Brunner, Mathias Madalinski, Dalia Barsyte-Lovejoy, Johannes A. Zuber, Manfred Koegl, Ralph A. Neumüller, Paola Martinelli

This study identifies BAP18 as a substrate of MAGE-A3/6, showing its degradation promotes cancer cell migration in both cell lines and human tissues.

bioRxiv · Mar 25, 2026 · PreprintCancer Biology

A journey towards developing a new cleavable crosslinker reagent for in-cell crosslinking

Fränze Müller, Bogdan R. Brutiu, Iakovos Saridakis, Thomas Leischner, Micha Johannes Birklbauer, Manuel Matzinger, Mathias Madalinski, Thomas Lendl, Saad Shaaban, Viktoria Dorfer, Nuno Maulide, Karl Mechtler

This paper introduces a new cleavable crosslinker, DiSPASO, for in-cell crosslinking and evaluates its performance in different model systems.

Communications Chemistry · Jun 23, 2025Peer-reviewedBiochemistry

Mimicked synthetic ribosomal protein complex for benchmarking cross-linking mass spectrometry workflows

Manuel Matzinger, Adrian Vasiu, Mathias Madalinski, Fränze Müller, Florian Stanek, Karl Mechtler

The paper introduces a synthetic peptide library and tool to benchmark cross-linking mass spectrometry workflows and demonstrates the importance of algorithm choice for improving identification rates and FDR.

Nature Communications · Jul 8, 2022Peer-reviewedBioinformatics