Pathogen infection induces sickness behaviors by recruiting neuromodulatory systems linked to stress and satiety in C. elegans
Sreeparna Pradhan, Gurrein K. Madan, Di Kang, Eric Bueno, Adam A. Atanas, Talya S Kramer, Ugur Dag, Jessica D. Lage, Matthew A. Gomes, Alicia Kun-Yang Lu, Jungyeon Park, Steven W. Flavell
This study identifies neuromodulatory systems involved in sickness behaviors in C. elegans infected with Pseudomonas aeruginosa, showing distinct roles of neuropeptides in regulating feeding, quiescence, and survival.
bioRxiv · Jan 5, 2024 · PreprintNeuroscience