Transgenic mice for in vivo epigenome editing with CRISPR-based systems
Matthew P. Gemberling, Keith Siklenka, Erica Rodriguez, Katherine R. Tonn Eisinger, Alejandro Barrera, Fang Liu, Ariel Kantor, Liqing Li, Valentina Cigliola, Mariah F. Hazlett, Courtney A. Williams, Luke C. Bartelt, Victoria J. Madigan, Josephine C. Bodle, Heather Daniels, , Charles A. Gersbach
This paper describes the generation of two transgenic mouse lines for in vivo epigenome editing using CRISPR-based systems to activate or repress gene expression.
bioRxiv · Mar 8, 2021 · PreprintGenomics