Bispecific antibody targeting of lipid nanoparticles
Angelo Amabile, Matthew Phelan, Zhe Yu, Pedro Silva, Adam R. Marks, Judit Morlà‐Folch, Moah Sohn, Gürkan Mollaoglu, Chiara Falcomatà, Abraham J. P. Teunissen, Joshua Brody, Yizhou Dong, Brian D. Brown
This paper develops a method to conjugate bispecific antibodies to lipid nanoparticles for targeted mRNA delivery, showing improved efficiency and specificity in transfecting specific cell types.
bioRxiv · Dec 20, 2024 · PreprintBioengineering