Author

Moah Sohn

Icahn School of Medicine at Mount SinaiORCID 0000-0002-3976-2091Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Organism:mouse· 1

Frequent Co-Authors

Brian D. BrowniD· 2 shared Joshua BrodyiD· 2 shared Abraham J. P. TeunisseniD· 1 shared Adam R. MarksiD· 1 shared Alan Cooper· 1 shared Angelo AmabileiD· 1 shared Chiara FalcomatàiD· 1 shared Daniel CharytonowicziD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Brian D. BrownORCID

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2 papers

Recent·Most cited

Potentiating CAR-T bystander killing by enhanced Fas/FasL signaling mitigates antigen escape in heterogeneous tumors

Matthew Junda Lin, Joanna K Chorazeczewski, Gvantsa Pantsulaia, Alan Cooper, Moah Sohn, Sidorela Reci, Jaime Mateus-Tique, Nicole H. Hirsh, Xin-Ping Xie, Ivan Odak, Rudra Prasad Dutta, Daniel Charytonowicz, Ranjan Upadhyay, Brian D. Brown, Miriam Mérad, , Joshua Brody

This study shows that enhancing Fas/FasL signaling improves CAR-T cell bystander killing against antigen-negative tumor cells, reducing antigen escape and improving therapeutic outcomes.

bioRxiv · Sep 22, 2025 · PreprintImmunology

Bispecific antibody targeting of lipid nanoparticles

Angelo Amabile, Matthew Phelan, Zhe Yu, Pedro Silva, Adam R. Marks, Judit Morlà‐Folch, Moah Sohn, Gürkan Mollaoglu, Chiara Falcomatà, Abraham J. P. Teunissen, Joshua Brody, Yizhou Dong, Brian D. Brown

This paper develops a method to conjugate bispecific antibodies to lipid nanoparticles for targeted mRNA delivery, showing improved efficiency and specificity in transfecting specific cell types.

bioRxiv · Dec 20, 2024 · PreprintBioengineering