Alcohol consumption drives sex- and region- specific disruption of somatostatin signaling in mice
Dakota F. Brockway, Keith R. Griffith, Andrew J. Kacala, Lauren Bellfy, Laurel R. Seemiller, Matthew Ulrich, Joseph M. Ricotta, Md Shakhawat Hossain, Janine L. Kwapis, Patrick J. Drew, Nicole A. Crowley
This study shows alcohol consumption disrupts somatostatin signaling in the prelimbic prefrontal cortex of mice, with potential implications for alcohol use disorder treatment.
bioRxiv · Jun 16, 2025 · PreprintNeuroscience