Author

Matthew Wakefield

Walter and Eliza Hall Institute of Medical Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew J. DeansiD· 1 shared Clare L. ScottiD· 1 shared Elaine SanijiD· 1 shared Jiachen Xuan· 1 shared Jian Kang· 1 shared Junqi Pan· 1 shared Karla J. CowleyiD· 1 shared Kaylene J. SimpsoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Andrew J. DeansORCID

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1 paper

Recent·Most cited

Local nucleolar surveillance mechanisms maintain rDNA stability

Ruofei Liu, Jiachen Xuan, Junqi Pan, Shalini Sundramurthi Chelliah, Rhynelle Dmello, Karla J. Cowley, Shannon Mendez, Yangyi Zhang, Kezia Gitareja, Matthew Wakefield, Andrew J. Deans, Clare L. Scott, Keefe T. Chan, Kaylene J. Simpson, Jian Kang, Elaine Sanij

This study identifies localized nucleolar surveillance mechanisms that respond to rDNA damage by activating the nucleolar DNA damage response (nDDR) through R-loop formation and RAD54L protection.

bioRxiv · Jan 20, 2025 · PreprintMolecular Biology