Amniotic fluid stem cell extracellular vesicles promote fetal lung branching and cell differentiation in experimental congenital diaphragmatic hernia
Kasra Khalaj, Rebeca Lopes Figueira, Lina Antounians, Sree Gandhi, Matthew Wales, Louise Montalva, George Biouss, Augusto Zani
This study shows that amniotic fluid stem cell extracellular vesicles rescue lung development in a rat model of congenital diaphragmatic hernia by restoring branching morphogenesis and cell differentiation.
bioRxiv · Jan 10, 2022 · PreprintDevelopmental Biology