Administration of amniotic fluid stem cell extracellular vesicles promotes development of fetal hypoplastic lungs by immunomodulating lung macrophages
Lina Antounians, Rebeca Lopes Figueira, Bharti Kukreja, Elke Zani‐Ruttenstock, Kasra Khalaj, Louise Montalva, Fabian Doktor, Mikal Obed, Matisse Blundell, Taiyi Wu, Cadia Chan, Richard Wagner, Martin Lacher, Michael D. Wilson, Brian Thomas Kalish, Augusto Zani
Amniotic fluid stem cell extracellular vesicles improve fetal lung development in CDH by modulating macrophage inflammation and restoring normal gene expression.
bioRxiv · Nov 29, 2022 · PreprintDevelopmental Biology