Modeling herpes simplex virus type 2 and Zika virus replication in vaginal organoids and spheroids
Ananya Saraph, Imogen Porter, Grace Bodykevich, Ingrid Barta, May Dang-Lawson, Maria Tokuyama
This study shows that vaginal organoids support HSV-2 and ZIKV replication and respond to antiviral drugs, with differences in drug efficacy between mouse organoids and human spheroids.
bioRxiv · Mar 3, 2026 · PreprintMicrobiology