Author

Md Rafikul Islam

University of Arkansas for Medical Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Md Mahbub Hasan· 2 shared Mohammad Alinoor RahmaniD· 2 shared Preeti NagariD· 2 shared Shabiha Afroj HeeamoniiD· 2 shared Adrian R. KraineriD· 1 shared Israt Jahan MuktaiD· 1 shared Mokarram HossainiD· 1 shared Naomi McNaughton· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Md Mahbub Hasan

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Author profile →

2 papers

Recent·Most cited

CRISPR-mediated Correction of Oncogenic AS-NMD in Splicing Factor Mutant Cancer

Preeti Nagar, Md Rafikul Islam, Nirjhor Anuvob Rahman, Shabiha Afroj Heeamoni, Md Mahbub Hasan, Saaimatul Huq, Rezwan Ali, Mokarram Hossain, Mohammad Alinoor Rahman

This paper demonstrates CRISPR-mediated correction of oncogenic AS-NMD in splicing factor mutant cancer by deleting a poison exon from the tumor suppressor EZH2.

bioRxiv · Jul 29, 2026 · PreprintCancer Biology

Targeting EZH2 Oncogenic Splicing: Decoding the Regulatory Network and Antisense Correction

Md Rafikul Islam, Preeti Nagar, Naomi McNaughton, Shabiha Afroj Heeamoni, Md Mahbub Hasan, Shila Kandel, Israt Jahan Mukta, Panagiotis Tsakiroglou, William Brian Dalton, Omar Ibrahim Abdel-Wahab, Adrian R. Krainer, Mohammad Alinoor Rahman

This study identifies splicing dysregulation in SF-mutated cancers and demonstrates that antisense oligonucleotides can correct aberrant splicing and restore tumor suppressor function.

bioRxiv · Jan 8, 2026Cancer Biology