Mohammad Alinoor Rahman

This study identifies splicing dysregulation in SF-mutated cancers and demonstrates that antisense oligonucleotides can correct aberrant splicing and restore tumor suppressor function.

This paper demonstrates CRISPR-mediated correction of oncogenic AS-NMD in splicing factor mutant cancer by deleting a poison exon from the tumor suppressor EZH2.

This study identifies FAM60A as a regulator of RNA splicing, showing it interacts with HDAC1 and spliceosome components, expanding its known role beyond the Sin3/HDAC complex.

The paper systematically characterizes short intronic splicing-regulatory elements by analyzing their effects on exon splicing using a minigene approach.

The paper develops a computational method, mCross, to model RBP binding specificity using precise crosslink site registration and validates it with ENCODE eCLIP data.