Spatial Logic Reconciles Gene-signature Methods in Triple Negative Breast Cancer
William C Bastian, Jane Lowe Meisel, Ji‐Hoon Lee, Nada Shaker, Lyra M. Griffiths, Meili Aiello, Zachary S. Buchwald, Yi Liu, E. Aubrey Thompson, Zaibo Li, Eugene F. Douglass, Xiaoxian Li
This study compares immune cell deconvolution and cancer subtype gene signatures in TNBC, finding that immune aggregates better predict outcomes than subtype signatures.
bioRxiv · Aug 18, 2026 · PreprintCancer Biology