Author

Melanie Gouley

Wellcome Sanger Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Synthetic Biology· 1

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Anant MaheshwariiD· 1 shared Elin Madli PeetsiD· 1 shared Fabio Giuseppe LiberanteiD· 1 shared Gareth GirlingiD· 1 shared Jacob HepkemaiD· 1 shared Jenie Hannah Johnkingsly Jebaraj· 1 shared Jonas KoeppeliD· 1 shared Juliane WelleriD· 1 shared

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1 shared paperSynthetic Biology

Anant MaheshwariORCID

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1 paper

Recent·Most cited

Resolution of a human super-enhancer by targeted genome randomisation

Jonas Koeppel, Pierre Murat, Gareth Girling, Elin Madli Peets, Melanie Gouley, Valentin Rebernig, Anant Maheshwari, Jacob Hepkema, Juliane Weller, Jenie Hannah Johnkingsly Jebaraj, Ronnie Crawford, Fabio Giuseppe Liberante, Leopold Parts

The paper uses enhancer scrambling to study a super-enhancer of the OTX2 gene, finding that a single DNase I hypersensitive site predominantly controls its expression.

bioRxiv · Jan 14, 2025 · PreprintSynthetic Biology