Author

Melanie Rittirsch

Friedrich Miescher Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Antoine H.F.M. PetersiD· 1 shared Daniel HeßiD· 1 shared Daniel OlivieriiD· 1 shared Eleonora Castelli· 1 shared Ilya LukoniniD· 1 shared Joerg BetschingeriD· 1 shared Michael Beda StadleriD· 1 shared Panagiotis PapasaikasiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Antoine H.F.M. PetersORCID

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1 paper

Recent·Most cited

REPRESSION BY HDAC3 AND DAX1 MEDIATES LINEAGE RESTRICTION OF EMBRYONIC STEM CELLS

Daniel Olivieri, Eleonora Castelli, Yumiko Kawamura, Panagiotis Papasaikas, Ilya Lukonin, Melanie Rittirsch, Daniel Heß, Sébastien A. Smallwood, Michael Beda Stadler, Antoine H.F.M. Peters, Joerg Betschinger

This study identifies Hdac3 and Dax1 as repressors that restrict mESCs from transdifferentiating into extraembryonic endoderm by silencing Gata6 enhancers, while Nr5a2 and Esrrb promote this conversion.

The EMBO Journal · Apr 28, 2021Peer-reviewedDevelopmental Biology