Author

Eleonora Castelli

Friedrich Miescher Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander W. RappiD· 1 shared Andreas MaiseriD· 1 shared Antoine H.F.M. PetersiD· 1 shared Daniel HeßiD· 1 shared Daniel OlivieriiD· 1 shared David M. GilbertiD· 1 shared Elin EnervaldiD· 1 shared Ilya LukoniniD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenomics

Alexander W. RappORCID

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2 papers

Recent·Most cited

Nuclear organisation and replication timing are coupled through RIF1-PP1 interaction

Stefano Gnan, Ilya M. Flyamer, Kyle N. Klein, Eleonora Castelli, Alexander W. Rapp, Andreas Maiser, Naiming Chen, Patrick Weber, Elin Enervald, M. Cristina Cardoso, Wendy A. Bickmore, David M. Gilbert, Sara B.C. Buonomo

This study identifies RIF1 as a molecular hub that co-regulates nuclear organisation and replication timing through its interaction with PP1, revealing distinct functional requirements for these processes.

Nature Communications · May 18, 2021Peer-reviewedGenomics

REPRESSION BY HDAC3 AND DAX1 MEDIATES LINEAGE RESTRICTION OF EMBRYONIC STEM CELLS

Daniel Olivieri, Eleonora Castelli, Yumiko Kawamura, Panagiotis Papasaikas, Ilya Lukonin, Melanie Rittirsch, Daniel Heß, Sébastien A. Smallwood, Michael Beda Stadler, Antoine H.F.M. Peters, Joerg Betschinger

This study identifies Hdac3 and Dax1 as repressors that restrict mESCs from transdifferentiating into extraembryonic endoderm by silencing Gata6 enhancers, while Nr5a2 and Esrrb promote this conversion.

The EMBO Journal · Apr 28, 2021Peer-reviewedDevelopmental Biology