Antoine H.F.M. Peters

The paper measures nucleosome occupancy in mouse and human sperm using single-molecule footprinting and finds species-specific differences in residual nucleosome retention.

This study shows that the eutherian-specific histone H3.4 variant promotes male germ cell development and reproductive fitness through specific sequence variations.

The paper introduces a statistical model for analyzing single-molecule footprinting data to infer footprint lengths and positions, validated on NOMe-seq datasets from mouse embryonic stem cells.

This study shows that paternal DNA methylation affects nucleosome retention in sperm and H3K4 methylation deposition in early embryos.

The paper assesses DNA accessibility in human sperm using NicE-view, finding two sub-populations with varying accessibility linked to reproductive outcomes.

This study shows that KDM2A and KDM2B prevent aberrant DNA methylation in mouse oocytes, which is critical for early embryonic development.

This study identifies H3K27me3's role in regulating genome-nuclear lamina interactions and allelic asymmetry during early mouse embryogenesis through single-cell LAD profiling and chromatin state analysis.

This study identifies Hdac3 and Dax1 as repressors that restrict mESCs from transdifferentiating into extraembryonic endoderm by silencing Gata6 enhancers, while Nr5a2 and Esrrb promote this conversion.

This paper develops a method for high fidelity lineage tracing in mouse pre-implantation embryos using primed conversion of photoconvertible proteins and light-sheet imaging.