Author

Melissa Galloux

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Dylan Caylor· 2 shared Eileen A. Southon· 2 shared Francesco Tomassoni‐ArdoriiD· 2 shared Lino TessarolloiD· 2 shared Shyam K. SharaniD· 2 shared Sounak SahuiD· 2 shared Teresa L. SullivaniD· 2 shared Arun Prakash MishraiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersGenetics

Dylan Caylor

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A single BRCA2 BRC repeat supports viability while multiple repeats ensure resilience under stress

Arun Prakash Mishra, Sounak Sahu, Satheesh Kumar Sengodan, Gemma Moore, Swati Priya, Natasha Oberoi, Julia R. Jensen, Eileen A. Southon, Melissa Galloux, Dylan Caylor, Teresa L. Sullivan, Sandra Sczerba Burkett, Mary E. Albaugh, Parirokh P. Awasthi, Francesco Tomassoni‐Ardori, , Shyam K. Sharan

This study shows that a single BRC repeat supports viability in mice but multiple repeats enhance resilience under oxidative stress.

bioRxiv · Jan 8, 2026 · PreprintGenetics

Clusters of deep intronic RbFox motifs embedded in large assembly of splicing regulators sequences regulate alternative splicing

Francesco Tomassoni‐Ardori, Mary Ellen Palko, Melissa Galloux, Lino Tessarollo

The paper identifies clustered RbFox motifs in introns that regulate alternative splicing by forming complexes with LASR sequences, showing their importance in gene expression and potential for pathogenic mutation identification.

PLoS Genetics · Sep 9, 2025Peer-reviewedGenetics

AVENGERS: Analysis of Variant Effects using Next Generation sequencing to Enhance BRCA2 Stratification

Sounak Sahu, Melissa Galloux, Eileen A. Southon, Dylan Caylor, Teresa L. Sullivan, Matteo Arnaudi, Josephine Geh, Raj Chari, Elena Papaleo, Shyam K. Sharan

The paper develops AVENGERS, a method using CRISPR-Cas9 to classify BRCA2 variants as functional or nonfunctional, improving the interpretation of variants of uncertain significance.

bioRxiv · Dec 14, 2023 · PreprintGenetics