Author

Arun Prakash Mishra

National Cancer InstituteORCID 0000-0001-6558-1166Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Satheesh Kumar SengodaniD· 2 shared Shyam K. SharaniD· 2 shared Dillon Dierman· 1 shared Dylan Caylor· 1 shared Eileen A. Southon· 1 shared Francesco Tomassoni‐ArdoriiD· 1 shared Gemma MooreiD· 1 shared Julia R. Jensen· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersGenetics

Satheesh Kumar SengodanORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintJan 8, 2026

A single BRCA2 BRC repeat supports viability while multiple repeats ensure resilience under stress

Arun Prakash Mishra, Sounak Sahu, Satheesh Kumar Sengodan…·Shyam K. Sharan

This study shows that a single BRC repeat supports viability in mice but multiple repeats enhance resilience under oxidative stress.

DOI 10.64898/2026.01.07.698272

mouseexperimental assay

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Cancer BiologyJournal of Biological ChemistryPeer-reviewedJun 19, 2025

5hmC enhances PARP trapping and restores PARP inhibitor sensitivity in chemoresistant BRCA1/2-deficient cells

Suhas S. Kharat, Arun Prakash Mishra, Satheesh Kumar Sengodan…·Shyam K. Sharan

This study shows that 5hmC increases PARP1 trapping on chromatin in olaparib-treated cells, restoring PARP inhibitor sensitivity in BRCA1/2-deficient cancer cells.

5 citations

humanDNA methylation

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