Parirokh Awasthi

This study shows that a single BRC repeat supports viability in mice but multiple repeats enhance resilience under oxidative stress.

The paper shows that a weak SLP-76-PLC-γ1 interaction fine-tunes TCR signal strength, optimizing T cell responsiveness by controlling PLC-γ1 activity.

The paper shows that disrupting chromatin domain boundaries with multiple developmental regulators can cause severe gene dysregulation and developmental defects in mice.

The paper shows AGO2 localizes to the nucleus in quiescent cells to silence mobile transposons via RNA interference.

The paper shows that high affinity enhancer-promoter interactions can bypass CTCF/cohesin insulation and maintain gene expression in some tissues but not others.