Author

Sandra Sczerba Burkett

National Institutes of HealthORCID 0000-0002-5476-4028Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Organism:human· 1

Frequent Co-Authors

Lino TessarolloiD· 2 shared Arun Prakash MishraiD· 1 shared Aydın BuluçiD· 1 shared Baktiar O. KarimiD· 1 shared Brad L. JakubisoniD· 1 shared Can Kızılkale· 1 shared Charli Gruen· 1 shared Chi-Ping DayiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersGenetics

Lino TessarolloORCID

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Author profile →

3 papers

Recent·Most cited

A single BRCA2 BRC repeat supports viability while multiple repeats ensure resilience under stress

Arun Prakash Mishra, Sounak Sahu, Satheesh Kumar Sengodan, Gemma Moore, Swati Priya, Natasha Oberoi, Julia R. Jensen, Eileen A. Southon, Melissa Galloux, Dylan Caylor, Teresa L. Sullivan, Sandra Sczerba Burkett, Mary E. Albaugh, Parirokh P. Awasthi, Francesco Tomassoni‐Ardori, , Shyam K. Sharan

This study shows that a single BRC repeat supports viability in mice but multiple repeats enhance resilience under oxidative stress.

bioRxiv · Jan 8, 2026 · PreprintGenetics

Id1 Promotes Clonal Hematopoiesis in Mice with Tet2 Loss of Function

Shweta Singh, Kristbjorn O. Gudmundsson, Tanmoy Sarkar, Brad L. Jakubison, Holly M. Morris, Sandra Sczerba Burkett, Baktiar O. Karim, Gary T. Pauly, Dina M. Sigano, Joel P. Schneider, Lino Tessarollo, Jonathan R. Keller

Genetic ablation of Id1 in Tet2-/- mice reduces clonal hematopoiesis by increasing CDKI expression, apoptosis, senescence, and differentiation while decreasing cell growth.

Science Advances · Aug 29, 2025Peer-reviewedCancer Biology

Profiles of expressed mutations in single cells reveal subclonal expansion patterns and therapeutic impact of intratumor heterogeneity

Farid Rashidi Mehrabadi, Kerrie L. Marie, Eva Pérez‐Guijarro, Salem Malikić, Erfan Sadeqi Azer, Howard H. Yang, Can Kızılkale, Charli Gruen, Welles Robinson, Huaitian Liu, Michael C. Kelly, Christina Marcelus, Sandra Sczerba Burkett, Aydın Buluç, Funda Ergün, , S. Cenk Şahinalp

Trisicell infers subclonal expansion patterns and therapeutic impact of intratumor heterogeneity from scRNAseq data, revealing correlations between mutational composition and tumor aggressiveness.

bioRxiv · Mar 26, 2021 · PreprintBioinformatics