Lino Tessarollo

This study shows that a single BRC repeat supports viability in mice but multiple repeats enhance resilience under oxidative stress.

The paper identifies clustered RbFox motifs in introns that regulate alternative splicing by forming complexes with LASR sequences, showing their importance in gene expression and potential for pathogenic mutation identification.

This study shows that Pde5a deficiency prevents diet-induced obesity by enhancing adipose cAMP-PKA activation, leading to fat browning and improved metabolic outcomes.

Genetic ablation of Id1 in Tet2-/- mice reduces clonal hematopoiesis by increasing CDKI expression, apoptosis, senescence, and differentiation while decreasing cell growth.

This paper uses a novel mouse model to identify new RanBP9 interactions in lung macrophages, revealing its role in immune and metabolic functions.

This study identifies Phox2a as a marker for anterolateral system neurons in mice and humans, showing their role in nociceptive signal relay and conservation across species.

This study investigates the role of Zfp423 in cerebellar neurogenesis, revealing its domain-specific effects on cell cycle progression, DNA damage response, and Purkinje cell development in mouse models.