Author

Merced Leiker

University at Buffalo, State University of New York

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Amir Ostadi MoghaddamiD· 1 shared Animesh A. SinhaiD· 1 shared Bahareh Tajvidi SafaiD· 1 shared Changjin HuangiD· 1 shared Daniel E. ConwayiD· 1 shared Elijah Jones· 1 shared Eunju KimiD· 1 shared Fanben MengiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Amir Ostadi MoghaddamORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Desmosomal Cadherin Tension Loss in Pemphigus Vulgaris Mediated by the Inhibition of Active RhoA at Cell-Cell Adhesions

Xiaowei Jin, Jordan Rosenbohm, Eunju Kim, Bahareh Tajvidi Safa, Amir Ostadi Moghaddam, Kristina Seiffert-Sinha, Merced Leiker, Elijah Jones, Haiwei Zhai, Sindora R. Baddam, Grayson Minnick, Yucheng Huo, James K. Wahl, Fanben Meng, Changjin Huang, , Ruiguo Yang

This study shows that PV antibodies cause tension loss at desmosomes and cell-cell adhesions by inhibiting RhoA, which can be partially reversed by altering actomyosin contractility.

iScience · Jul 15, 2025Peer-reviewedBiophysics