Haiwei Zhai

Human Cytomegalovirus Infects and Remodels 3D-biofabricated Skin Equivalents

This study infects and evaluates HCMV in a 3D biofabricated skin model, showing productive infection and reduced viral transit in 3D cultures compared to 2D.

Data-Driven Image Analysis to Determine Antibody-Induced Dissociation of Cell-Cell Adhesion and Antibody Pathogenicity in Pemphigus Vulgaris

This paper introduces a data-driven image analysis approach to quantify antibody-induced changes in cell-cell adhesion and pathogenicity in pemphigus vulgaris.

Desmosomal Cadherin Tension Loss in Pemphigus Vulgaris Mediated by the Inhibition of Active RhoA at Cell-Cell Adhesions

This study shows that PV antibodies cause tension loss at desmosomes and cell-cell adhesions by inhibiting RhoA, which can be partially reversed by altering actomyosin contractility.