Modulating SPARC Expression in Mesenchymal Stem Cells Improves Secretome-Mediated Skin Regeneration and Wound Repair
Antonella Lombardi, Joaquín Smucler, María Belén Palma, Ailén Iribarne, Alejandro La Greca, Mercedes García, Gustavo Emilio Sevlever, Santiago Miriuka, Carlos Luzzani
This study shows that increasing SPARC expression in mesenchymal stem cells enhances their secretome's ability to promote skin regeneration and wound healing.
bioRxiv · Mar 9, 2026 · PreprintCell Biology