Identification of a Neuroimmune Circuit that Regulates Allergic Inflammation in the Esophagus
Kendall M. Kellerman, Mark Rochman, Mia A Natale, Edward Gerstner, Yrina Rochman, Tamara Golosarsky, Julie M. Caldwell, Jennifer M. Felton, Michael P. Jankowski, Marc E. Rothenberg
This study identifies a type 2 neuroimmune circuit involving IL-4 receptor-dependent DRG responses that modify esophageal inflammation in eosinophilic esophagitis.
Nature Communications · Oct 16, 2026Peer-reviewedImmunology