Programmable RNA Sensing for Cell Monitoring and Manipulation
Yongjun Qian, Jiayun Li, Shengli Zhao, Elizabeth A. Matthews, Michael Adoff, Weixin Zhong, Xu An, Michele Yeo, Christine Park, Xiaolu Yang, Bor‐Shuen Wang, Derek G. Southwell, Z. Josh Huang
This paper introduces CellREADR, a programmable RNA sensing technology that detects and manipulates cell types via RNA editing, demonstrating its use in mouse and human brain tissues.
Nature · Oct 5, 2022Peer-reviewedMolecular Biology