Author

Michele Yeo

Duke Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Assay:multiome· 1 Research Focus:protein design· 1

Frequent Co-Authors

Andrey V. BortsoviD· 1 shared Bor‐Shuen WangiD· 1 shared Changyu JiangiD· 1 shared Christine ParkiD· 1 shared Derek G. SouthwelliD· 1 shared Elizabeth A. MatthewsiD· 1 shared Gang CheniD· 1 shared Jiayun LiiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Andrey V. BortsovORCID

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2 papers

Recent·Most cited

Programmable RNA Sensing for Cell Monitoring and Manipulation

Yongjun Qian, Jiayun Li, Shengli Zhao, Elizabeth A. Matthews, Michael Adoff, Weixin Zhong, Xu An, Michele Yeo, Christine Park, Xiaolu Yang, Bor‐Shuen Wang, Derek G. Southwell, Z. Josh Huang

This paper introduces CellREADR, a programmable RNA sensing technology that detects and manipulates cell types via RNA editing, demonstrating its use in mouse and human brain tissues.

Nature · Oct 5, 2022Peer-reviewedMolecular Biology

Repurposing cell growth-regulating compounds identifies kenpaullone which ameliorates pathologic pain via normalization of inhibitory neurotransmission

Michele Yeo, Yong Chen, Changyu Jiang, Gang Chen, Kaiyuan Wang, Andrey V. Bortsov, Maria Lioudyno, Qian Zeng, Zilong Wang, Jorge A. Busciglio, Ru‐Rong Ji, Wolfgang Liedtke

The paper identifies kenpaullone as a compound that enhances KCC2 expression and reduces pathologic pain by restoring inhibitory neurotransmission in mouse models.

bioRxiv · Mar 19, 2020 · PreprintNeuroscience