Two sample Mendelian Randomisation using an outcome from a multilevel model of disease progression
Michael Lawton, Yoav Ben‐Shlomo, Apostolos Gkatzionis, Michele T. Hu, Donald G. Grosset, Kate M. Tilling
The paper applies a multivariate two-sample Mendelian Randomisation approach to estimate causal effects on disease progression intercept and slope using Parkinson's cohorts.
European Journal of Epidemiology · Jan 28, 2024Peer-reviewedGenetic & Genomic Medicine