Elevated dietary ω-6 polyunsaturated fatty acids induce reversible peripheral nerve dysfunction that exacerbates comorbid pain conditions
Jacob T. Boyd, P.M. Lococo, Ashley R. Furr, Michelle Bendele, Meilinn Tram, Qun Li, Fang-Mei Chang, Madeline E. Colley, Grace M. Samenuk, Dominic Arris, Erin E. Locke, Stephan B. H. Bach, Alejandro Tobon, Shivani B. Ruparel, Kenneth Hargreaves
This study shows that a high ω-6 PUFA diet causes reversible peripheral nerve dysfunction and worsens pain in mice, with potential therapeutic implications.
Nature Metabolism · Jun 17, 2021Peer-reviewedNeuroscience