Shivani B. Ruparel

Investigating Mechanically Activated Currents from Trigeminal Neurons of Non-Human Primates

The paper characterizes mechanically activated currents in trigeminal neurons of non-human primates, identifying distinct neuronal subtypes and their functional properties.

Truncated TrkB: The predominant TrkB Isoform in Nociceptors

This study identifies TrkBT1 as the predominant TrkB isoform in sensory neurons, including nociceptors, and shows its functional role in modulating neuronal activity and survival.

Sensory innervation of masseter, temporal and lateral pterygoid muscles in common marmosets

This study examines sensory nerve types innervating masticatory muscles in common marmosets, finding distinct innervation patterns with differences in fiber types across muscle groups.

Transcriptional Profiles of Non-neuronal and Immune Cells in Mouse Trigeminal Ganglia

This study profiles non-neuronal and immune cells in mouse trigeminal ganglia using scRNA-seq, FC, and IHC, identifying and classifying cell types based on gene expression and markers.

Sex-dependent Differences in the Genomic Profile of Lingual Sensory Neurons in Naive and Tongue-Tumor Bearing Mice

The paper identifies sex-dependent differences in transcriptomic profiles of lingual sensory neurons in naive and tongue-tumor bearing mice.

Understanding Painful versus Non-Painful Dental Pain in Male and Female Patients: A Transcriptomic Analysis of Human Biopsies

The paper performs transcriptomic analysis of human dental biopsies to identify gene expression differences between symptomatic and asymptomatic patients and between sexes.

Elevated dietary ω-6 polyunsaturated fatty acids induce reversible peripheral nerve dysfunction that exacerbates comorbid pain conditions

This study shows that a high ω-6 PUFA diet causes reversible peripheral nerve dysfunction and worsens pain in mice, with potential therapeutic implications.