Author

Fang-Mei Chang

The University of Texas at San Antonio Health Science Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Shivani B. RupareliD· 4 shared Jaclyn MerloiD· 2 shared Ping WuiD· 2 shared Tarek IbrahimiD· 2 shared Zhao LaiiD· 2 shared Alejandro ToboniD· 1 shared Alexei V. TumanoviD· 1 shared Armen N. AkopianiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersNeuroscience

Shivani B. RuparelORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Truncated TrkB: The predominant TrkB Isoform in Nociceptors

Jaclyn Merlo, Fang-Mei Chang, Michael Tran, Jessie Alfaro, Tarek Ibrahim, Ping Wu, Shivani B. Ruparel

This study identifies TrkBT1 as the predominant TrkB isoform in sensory neurons, including nociceptors, and shows its functional role in modulating neuronal activity and survival.

Journal of Pain · Apr 23, 2025Peer-reviewedNeuroscience

Sex-dependent Differences in the Genomic Profile of Lingual Sensory Neurons in Naive and Tongue-Tumor Bearing Mice

Tarek Ibrahim, Ping Wu, Li‐Ju Wang, Fang-Mei Chang, Josue Murillo, Jaclyn Merlo, Sergey A. Shein, Alexei V. Tumanov, Zhao Lai, Korri S. Weldon, Yidong Chen, Shivani B. Ruparel

The paper identifies sex-dependent differences in transcriptomic profiles of lingual sensory neurons in naive and tongue-tumor bearing mice.

Scientific Reports · Aug 12, 2023Peer-reviewedNeuroscience

Understanding Painful versus Non-Painful Dental Pain in Male and Female Patients: A Transcriptomic Analysis of Human Biopsies

Biraj Patel, Michael Eskander, Fang-Mei Chang, Brett Chapa, Shivani B. Ruparel, Zhao Lai, Yidong Chen, Armen N. Akopian, Nikita B. Ruparel

The paper performs transcriptomic analysis of human dental biopsies to identify gene expression differences between symptomatic and asymptomatic patients and between sexes.

bioRxiv · Jan 26, 2023 · PreprintGenomics

Elevated dietary ω-6 polyunsaturated fatty acids induce reversible peripheral nerve dysfunction that exacerbates comorbid pain conditions

Jacob T. Boyd, P.M. Lococo, Ashley R. Furr, Michelle Bendele, Meilinn Tram, Qun Li, Fang-Mei Chang, Madeline E. Colley, Grace M. Samenuk, Dominic Arris, Erin E. Locke, Stephan B. H. Bach, Alejandro Tobon, Shivani B. Ruparel, Kenneth Hargreaves

This study shows that a high ω-6 PUFA diet causes reversible peripheral nerve dysfunction and worsens pain in mice, with potential therapeutic implications.

Nature Metabolism · Jun 17, 2021Peer-reviewedNeuroscience