State-dependent GABAergic regulation of striatal spiny projection neuron excitability
Michelle Day, Marziyeh Belal, William C. Surmeier, Alexandria Ellen Melendez-Zaidi, David L. Wokosin, Tatiana Tkatch, Vernon R. J. Clarke, Dalton James Surmeier
The paper investigates how GABAergic inputs modulate striatal spiny projection neuron excitability, showing that GABAARs can depolarize neurons in the resting down-state, enhancing responses to glutamatergic inputs.
PLoS Biology · Jan 31, 2024Peer-reviewedNeuroscience