AMPK/ULK1 activation downregulates TXNIP, Rab5, and Rab7 and inhibits endocytosis-mediated entry of human pathogenic viruses
Viktoria Diesendorf, Veronica La Rocca, Michelle Teutsch, Haisam Alattar, Helena Obernolte, Kornelia Kenst, Jens Seibel, Philipp Wörsdörfer, Katherina Sewald, Maria R. Steinke, Sibylle Schneider‐Schaulies, Manfred Bernhard Lutz, Mathias Munschauer, Jochen Bodem
This study shows that AMPK/ULK1 activation inhibits endocytosis and blocks viral entry by reducing key endocytic factors and endosomal markers.
Cells · Feb 24, 2025Peer-reviewedMicrobiology