Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy
Marina I. Oliveira da Silva, Miguel Santejo, Isaac William Babcock, Ana Magalhães, Laurie S. Minamide, Seok-Joon Won, Erika Castillo, Ellen Gerhardt, Christiane Fahlbusch, Raymond A. Swanson, Tiago F. Outeiro, Ricardo Jorge Ferreira Taipa, Michael R. Ruff, James R. Bamburg, Márcia A. Liz
This study identifies cofilin dysregulation as a mediator of α-synuclein-induced synaptic dysfunction in hippocampal neurons in synucleinopathy models.
Cell Death and Disease · Apr 13, 2024Peer-reviewedNeuroscience