Author

Isaac William Babcock

Colorado State UniversityORCID 0000-0003-0360-0821Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Abigail G. Kelly· 1 shared Ana MagalhãesiD· 1 shared Christiane Fahlbusch· 1 shared Ellen GerhardtiD· 1 shared Erika CastilloiD· 1 shared Ish SethiiD· 1 shared James R. BamburgiD· 1 shared John R. LukensiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Abigail G. Kelly

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2 papers

Recent·Most cited

ImmunologyPLoS PathogensPeer-reviewedOct 24, 2024

Caspase-1 in Cx3cr1-expressing cells drives an IL-18-dependent T cell response that promotes parasite control during acute T. gondii infection

Isaac William Babcock, Lydia Anne Sibley, Sydney A. Labuzan…·Tajie H. Harris

This study shows that caspase-1 in Cx3cr1-expressing cells drives IL-18 release, enhancing CD4+ T cell IFN-γ production and parasite control during acute T. gondii infection.

10 citations

mouseexperimental assay

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NeuroscienceCell Death and DiseasePeer-reviewedApr 13, 2024

Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy

Marina I. Oliveira da Silva, Miguel Santejo, Isaac William Babcock…·Márcia A. Liz

This study identifies cofilin dysregulation as a mediator of α-synuclein-induced synaptic dysfunction in hippocampal neurons in synucleinopathy models.

17 citations

mouseexperimental assay

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