Pharmacology & ToxicologybioRxiv
Large- and Small-Animal Studies of Safety, Pharmacokinetics (PK), and Biodistribution of Inflammasome-Targeting Nanoligomer in the Brain and Other Target Organs
Sydney Risen, Sadhana Sharma, Vincenzo S. Gilberto…·Prashant Nagpal
This paper evaluates the safety, pharmacokinetics, and biodistribution of an inflammasome-targeting Nanoligomer cocktail in small and large animals across multiple administration routes.