Jared M. Brown

This study shows that micro- and nanoplastics disrupt human brain development and function by inducing inflammation, cellular senescence, and altered electrophysiological activity.

This paper shows that targeting neuroinflammation by down-regulating NF-κB and NLRP3 with SB_NI_112 protects against neurodegeneration in prion disease models.

This paper evaluates the safety, pharmacokinetics, and biodistribution of an inflammasome-targeting Nanoligomer cocktail in small and large animals across multiple administration routes.