Gut microbiota gate host exposure to cholinesterase inhibitors from dietary Solanums
Catherine S. Liou, Tijs Louwies, Mikhail Iakiviak, Jakub Rajniak, Pallavi P. Murugkar, Steven Kyle Higginbottom, Allison M. Weakley, Xiandong Meng, Phyu Htet, Ashley V. Cabrera, Marissa Jasper, Alex Dimas, E. A. Schulman, Michael Andrew Fischbach, Purna Kashyap, Elizabeth S. Sattely
The paper investigates how gut microbiota modify steroidal alkaloids from Solanum plants, affecting host exposure and physiological effects.
bioRxiv · Mar 20, 2024 · PreprintMicrobiology