Development of antigen-dextramers for detection and evaluation of CAR T cells
Rasmus U. W. Friis, Maria Ormhøj, Cecilie S. Krüger-Jensen, Carlos Rodriguez Pardo, Hólmfridur R. Halldórsdóttir, Markus Barden, Nikolaj Pagh Kristensen, Keerthana Ramanathan, Mikkel R. Hansen, Hinrich Abken, Sine Reker Hadrup
This paper develops antigen-dextramers to stain and functionally assess CAR T cells, showing they enable both detection and activation analysis with adjustable antigen density.
Cancer Immunology Immunotherapy · Oct 23, 2025Peer-reviewedBioengineering